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1

Kinetic Mechanism of the 3‘ → 5‘ Proofreading Exonuclease of DNA Polymerase III. Analysis by Steady State and Pre-Steady State Methods †

Miller, Holly, Perrino, Fred W.

Journal:

Year:

1996

Language:

english

File:

PDF, 355 KB

english, 1996

2

Eucaryotic DNA Primase Does Not Prefer To Synthesize Primers at Pyrimidine Rich DNA Sequences When Nucleoside Triphosphates Are Present at Concentrations Found in Whole Cells †

Kirk, Brian W., Harrington, Cindy, Perrino, Fred W., Kuchta, Robert D.

Journal:

Year:

1997

Language:

english

File:

PDF, 179 KB

english, 1997

3

The exonuclease TREX2 shapes psoriatic phenotype

Manils, Joan, Eduard, Casas, Viña-Vilaseca, Arnau, López-Cano, Marc, Díez-Villanueva, Anna, Gómez, Diana, Marruecos, Laura, Ferran, Marta, Benito, Carmen, Perrino, Fred W., Vavouri, Tanya, Maria de An

Journal:

The Journal of Investigative Dermatology

Year:

2016

Language:

english

File:

PDF, 4.03 MB

english, 2016

4

The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch

Mauney, Christopher H., Rogers, LeAnn C., Harris, Reuben S., Daniel, Larry W., Devarie-Baez, Nelmi O., Wu, Hanzhi, Furdui, Cristina M., Poole, Leslie B., Perrino, Fred W., Hollis, Thomas

Journal:

Antioxidants & Redox Signaling

Year:

2017

Language:

english

File:

PDF, 3.13 MB

english, 2017

5

Heterozygous Mutations in TREX1 Cause Familial Chilblain Lupus and Dominant Aicardi-Goutières Syndrome

Gillian Rice, William G. Newman, John Dean, Teresa Patrick, Rekha Parmar, Kim Flintoff, Peter Robins, Scott Harvey, Thomas Hollis, Ann O’Hara, Ariane L. Herrick, Andrew P. Bowden, Fred W. Perrino, Tom

Journal:

The American Journal of Human Genetics

Year:

2007

Language:

english

File:

PDF, 2.33 MB

english, 2007

6

Polymerization Past the N 2 -Isopropylguanine and the N 6 -Isopropyladenine DNA Lesions with the Translesion Synthesis DNA Polymerases η and ι and the Replicative DNA Polymerase α †

Perrino, Fred W., Harvey, Scott, Blans, Patrick, Gelhaus, Stacy, LaCourse, William R., Fishbein, James C.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 822 KB

english, 2005

7

RNaseH2 mutants that cause Aicardi–Goutieres syndrome are active nucleases

Fred W. Perrino, Scott Harvey, Nadine M. Shaban, Thomas Hollis

Journal:

Journal of Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 226 KB

english, 2009

8

An EPR study to determine the relative nucleic acid binding affinity of single-stranded DNA-binding protein from Escherichia coli

Elisabeth V. Bobst, Fred W. Perrino, Ralph R. Meyer, Albert M. Bobst

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1991

File:

PDF, 802 KB

1991

9

Spatial and temporal distribution of polycyclic aromatic hydrocarbons and elemental carbon in Bakersfield, California

Noth, Elizabeth M., Lurmann, Fred, Northcross, Amanda, Perrino, Charles, Vaughn, David, Hammond, S. Katharine

Journal:

Air Quality, Atmosphere & Health

Year:

2016

Language:

english

File:

PDF, 758 KB

english, 2016

10

Dysfunctional proofreading in the Escherichia coli DNA polymerase III core

LEHTINEN, Duane A., PERRINO, Fred W.

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 352 KB

english, 2004

11

Animal cell DNA polymerases in DNA repair

Perrino, Fred W., Loeb, Lawrence A.

Journal:

Mutation Research/DNA Repair

Year:

1990

Language:

english

File:

PDF, 1.04 MB

english, 1990

12

Elucidation of the ε−θ Subunit Interface of Escherichia coli DNA Polymerase III by NMR Spectroscopy †

DeRose, Eugene F., Darden, Thomas, Harvey, Scott, Gabel, Scott, Perrino, Fred W., Schaaper, Roel M., London, Robert E.

Journal:

Year:

2003

Language:

english

File:

PDF, 605 KB

english, 2003

13

Mutagenesis by exocyclic alkylamino purine adducts in Escherichia coli

Dana C. Upton, Xueying Wang, Patrick Blans, Fred W. Perrino, James C. Fishbein, Steven A. Akman

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2006

Language:

english

File:

PDF, 243 KB

english, 2006

14

Appointments.

Perrino, Fred W., Loeb, Lawrence A.

Journal:

Year:

1896

Language:

english

File:

PDF, 210 KB

english, 1896

15

The Exonuclease TREX1 Is in the SET Complex and Acts in Concert with NM23-H1 to Degrade DNA during Granzyme A-Mediated Cell Death

Dipanjan Chowdhury, Paul J. Beresford, Pengcheng Zhu, Dong Zhang, Jung-Suk Sung, Bruce Demple, Fred W. Perrino, Judy Lieberman

Journal:

Year:

2006

Language:

english

File:

PDF, 552 KB

english, 2006

16

Mammalian DNA Polymerases .alpha., .beta., .gamma., .delta., and .epsilon. Incorporate Fialuridine (FIAU) Monophosphate into DNA and Are Inhibited Competitively by FIAU Triphosphate

Lewis, William, Meyer, Ralph R., Simpson, James F., Colacino, Joseph M., Perrino, Fred W.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.16 MB

english, 1994

17

A preliminary CD and NMR study of the Escherichia coli DNA polymerase III Θ subunit

Dawei Li, Devon L. Allen, Scott Harvey, Fred W. Perrino, Roel M. Schaaper, Robert E. London

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1999

Language:

english

File:

PDF, 144 KB

english, 1999

18

Model for the Catalytic Domain of the Proofreading ε Subunit of Escherichia coli DNA Polymerase III Based on NMR Structural Data †

DeRose, Eugene F., Li, Dawei, Darden, Thomas, Harvey, Scott, Perrino, Fred W., Schaaper, Roel M., London, Robert E.

Journal:

Year:

2002

Language:

english

File:

PDF, 639 KB

english, 2002

19

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 â¢ New Orleans - ()] C48. EXPOSURE ASSESSMENT AND INTERVENTIONS IN ENVIRONMENTAL OCCUPATIONAL HEALTH - Measurement And Distribution Of Ambient PAHs In Fresno, CA

Hammond, S Katharine, Noth, Elizabeth, Gundel, Laura, Perrino, Charles, Lurmann, Fred, Tager, Ira

Year:

2010

File:

PDF, 18 KB

2010

20

A mutation inTREX1that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus

Min Ae Lee-Kirsch, Dipanjan Chowdhury, Scott Harvey, Maoliang Gong, Lydia Senenko, Kerstin Engel, Christiane Pfeiffer, Thomas Hollis, Manfred Gahr, Fred W. Perrino, Judy Lieberman, Norbert Hubner

Journal:

Journal of Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 206 KB

english, 2007

21

Sequence specificity of pausing by DNA polymerases

Pnina Weisman-Shomer, Dipak K. Dube, Fred W. Perrino, Karen Stokes, Lawrence A. Loeb, Michael Fry

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 1.89 MB

english, 1989

22

[Lupus Foundation of America 13th International Congress on Systemic Lupus Erythematosus (LUPUS 2019), San Francisco, California, USA, April 5â8, 2019, Abstract Presentations - ()] Abstracts - 284âT cells produce interferon alpha in a model of lupus-like disease

Simpson, Sean, Rego, Stephen, Harvey, Scott, Grayson, Jason, Perrino, Fred

Year:

2019

File:

PDF, 221 KB

2019

23

WRN exonuclease activity is blocked by DNA termini harboring 3′ obstructive groups

Jeanine A. Harrigan, Jinshui Fan, Jamil Momand, Fred W. Perrino, Vilhelm A. Bohr, David M. Wilson III

Journal:

Mechanisms of Ageing and Development

Year:

2007

Language:

english

File:

PDF, 495 KB

english, 2007

24

T Cells Produce IFN-Î± in the TREX1 D18N Model of Lupus-like Autoimmunity

Simpson, Sean R., Rego, Stephen L., Harvey, Scott E., Liu, Mingyong, Hemphill, Wayne O., Venkatadri, Rajkumar, Sharma, Rahul, Grayson, Jason M., Perrino, Fred W.

Journal:

The Journal of Immunology

Year:

2020

File:

PDF, 1.95 MB

2020

25

Replication of N 2 -Ethyldeoxyguanosine DNA Adducts in the Human Embryonic Kidney Cell Line 293

Upton, Dana C., Wang, Xueying, Blans, Patrick, Perrino, Fred W., Fishbein, James C., Akman, Steven A.

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 200 KB

english, 2006

26

The Multidimensional Nature of Antiviral Innate Immunity

Harris, Reuben S., Perrino, Fred W., Shaban, Nadine M.

Journal:

Cell Host & Microbe

Year:

2015

Language:

english

File:

PDF, 295 KB

english, 2015

27

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

Grieves, Jessica L., Fye, Jason M., Harvey, Scott, Grayson, Jason M., Hollis, Thomas, Perrino, Fred W.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

28

Initiation of RNA-primed DNA synthesis in vitro by DNA polymerase α-primase

Harrington, Cindy, Perrino, Fred W.

Journal:

Nucleic Acids Research

Year:

1995

Language:

english

File:

PDF, 7.82 MB

english, 1995

29

TREX1 â Apex predator of cytosolic DNA metabolism

Simpson, Sean R., Hemphill, Wayne O., Hudson, Teesha, Perrino, Fred W.

Journal:

Year:

2020

File:

PDF, 1.67 MB

2020

30

The relative rate of synthesis and levels of single-stranded DNA binding protein during induction of SOS repair inEscherichia coli

Fred W. Perrino, Diane C. Rein, Albert M. Bobst, Ralph R. Meyer

Journal:

Molecular Genetics and Genomics

Year:

1987

Language:

english

File:

PDF, 303 KB

english, 1987

31

Bypass of N2-ethylguanine by human DNA polymerase κ

Matthew G. Pence, Patrick Blans, Charles N. Zink, James C. Fishbein, Fred W. Perrino

Journal:

Year:

2011

Language:

english

File:

PDF, 724 KB

english, 2011

32

Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease

Suzanna L. Bailey, Scott Harvey, Fred W. Perrino, Thomas Hollis

Journal:

Year:

2012

Language:

english

File:

PDF, 1.46 MB

english, 2012

33

Proofreading by the ε Subunit of Escherichia coli DNA Polymerase III Increases the Fidelity of Calf Thymus DNA Polymerase α

Fred W. Perrino and Lawrence A. Loeb

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.11 MB

english, 1989

34

Crystal structure of RNA-DNA duplex provides insight into conformational changes induced by RNase H binding

Davis, Ryan R, Shaban, Nadine M, Perrino, Fred W, Hollis, Thomas

Journal:

Year:

2015

Language:

english

File:

PDF, 733 KB

english, 2015

35

Sequence variants in the 3′→5′ deoxyribonuclease TREX2: identification in a genetic screen and effects on catalysis by the recombinant proteins

Fred W. Perrino, Anna Krol, Scott Harvey, S.Lilly Zheng, David A. Horita, Thomas Hollis, Deborah A. Meyers, William B. Isaacs, Jianfeng Xu

Journal:

Advances in Enzyme Regulation

Year:

2004

Language:

english

File:

PDF, 304 KB

english, 2004

36

Extension of Mismatched 3′Termini of DNA is a Major Determinant of the Infidelity of Human Immunodeficiency Virus Type 1 Reverse Transcriptase

Fred W. Perrino, Bradley D. Preston, Lisa L. Sandell and Lawrence A. Loeb

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1016 KB

english, 1989

37

Fialuridine and its Metabolites Inhibit DNA Polymerase γ at Sites of Multiple Adjacent Analog Incorporation, Decrease mtDNA Abundance, and Cause Mitochondrial Structural Defects in Cultured Hepatoblasts

William Lewis, Eric S. Levine, Brone Griniuviene, Kevin O. Tankersley, Joseph M. Colacino, Jean-Pierre Sommadossi, Kyoichi A. Watanabe and Fred W. Perrino

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.56 MB

english, 1996

38

Identification of inhibitors of the dNTP triphosphohydrolase SAMHD1 using a novel and direct high throughput assay.

Mauney, Christopher, Perrino, Dr. Fred W., Hollis, Thomas

Journal:

Year:

2018

Language:

english

File:

PDF, 1.22 MB

english, 2018

39

Hydrolysis of 3'-terminal mispairs in vitro by the 3' .fwdarw. 5' exonuclease of DNA polymerase .delta. permits subsequent extension by DNA polymerase .alpha.

Perrino, Fred W., Loeb, Lawrence A.

Journal:

Year:

1990

Language:

english

File:

PDF, 2.07 MB

english, 1990

40

The N 2 -Ethylguanine and the O 6 -Ethyl- and O 6 -Methylguanine Lesions in DNA: Contrasting Responses from the “Bypass” DNA Polymerase η and the Replicative DNA Polymerase α

Perrino, Fred W., Blans, Patrick, Harvey, Scott, Gelhaus, Stacy L., McGrath, Colleen, Akman, Steven A., Jenkins, G. Scott, LaCourse, William R., Fishbein, James C.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 161 KB

english, 2003

41

TREX1 D18N mice fail to process erythroblast DNA resulting in inflammation and dysfunctional erythropoiesis

Rego, Stephen L., Harvey, Scott, Simpson, Sean R., Hemphill, Wayne O., McIver, Zachariah A., Grayson, Jason M., Perrino, Fred W.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.82 MB

english, 2018

42

Proof-reading 3′→5′ exonucleases isolated from rat liver nuclei

Natalya V. BELYAKOVA, Natalya E. KLEINER, Tatyana P. KRAVETSKAYA, Olga K. LEGINA, Stanislav N. NARYZHNY, Fred W. PERRINO, Igor V. SHEVELEV, Valery M. KRUTYAKOV

Journal:

Year:

1993

Language:

english

File:

PDF, 719 KB

english, 1993

43

Two Functional Domains of the ε Subunit of DNA Polymerase III †

Perrino, Fred W., Harvey, Scott, McNeill, S. Mark

Journal:

Year:

1999

Language:

english

File:

PDF, 313 KB

english, 1999

44

Solid-state nanopore analysis of diverse DNA base modifications using a modular enzymatic labeling process

Wang, Fanny, Zahid, Osama K, Swain, Brandi, Parsonage, Derek, Hollis, Thomas, Harvey, Scott, Perrino, Dr. Fred, Kohli, Rahul M, Taylor, Ethan W, Hall, Adam R.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.49 MB

english, 2017

45

Decrease in ambient polycyclic aromatic hydrocarbon concentrations in California's San Joaquin Valley 2000â2019

Noth, Elizabeth M., Lurmann, Fred, Perrino, Charles, Vaughn, David, Minor, Hilary A., Hammond, S. Katharine

Journal:

Atmospheric Environment

Year:

2020

File:

PDF, 3.04 MB

2020

46

Exonucleases and the incorporation of aranucleotides into DNA

Fred W. Perrino, Dan J. Mazur, Heather Ward, Scott Harvey

Journal:

Cell Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 2.39 MB

english, 1999

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